
From the book, i saw the opened loop system and the closed loop system of insulin administration. The book didn't explain much on it. What is meant by the "opened" and "closed" actually? How these things work? Can someone give me a brief and understandable explanation? Thank you.
Ben Trolled - An open-loop insulin delivery system
ReplyDeletecombines an external insulin pump with
continuous monitoring of glucose levels via a
subcutaneous sensor. The sensor
communicates glucose readings to the pump
using a radio transmitter.
External subcutaneous closed-loop and implantable
closed-loop systems are under development.36 An
implantable system would deliver insulin into the
peritoneum. This is advantageous because rapid
absorption and direct delivery to the hepatic circulation
could occur.37 Although less invasive, there is a delay in
insulin absorption and action with the subcutaneous
closed-loop system, which may limit its use.38 The results
from initial studies of subcutaneous and fully implantable
closed-loop insulin delivery systems are promising.39-41
The insulin pump component of the implantable closedloop
system is available in Europe.42
Takae care
Ben Trolled